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Red Yeast Rice is rice that is fermented with the yeast Monascus purpureus. There are many strains of the yeast Monascus purpureus, and one of them, the 'Went' strain, when appropriately fermented, yields 0.4% monacolin K.
Research has found Red Yeast Rice to be as effective as and in certain cases more effective than cholesterol lowering drugs. Unived's RYR is a natural product, standardized to 0.4% monacolin K, the international standard for safe, cholesterol lowering Red Yeast Rice.
Natural RYR vs synthetic cholesterol lowering drugs
Red Yeast Rice is a traditional Chinese concept demonstrated through several studies, to lower lipid levels. Red Yeast Rice, also known as Monascus purpureus rice, is derived from the 'Went' strain of M. pupureus, and is prepared by the traditional rice fermentation method. Synthetic cholesterol lowering drugs came into the market in the late 70s when the cholesterol lowering agent was isolated by scientists from the Aspergillus oryzae. Monascus and Aspergillus were both being studied at the same time.
Chemical structure and composition
Monacolin K is the key ingredient of Red Yeast Rice whereas it's also the key ingredient of some synthetic cholesterol lowering drugs. A popular cholesterol lowering drug and monacolin K have an identical chemical structure and both work as HMG-CoA reductase inhibitors causing inhibition of cholesterol synthesis in the liver.
However unlike synthetic cholesterol lowering drugs, Red Yeast Rice also contains nutritional elements such as proteins, sterols, isoflavone and its glycosides, unsaturated fatty acids, saponin and sapogenins and some trace elements – these enhance the cholesterol lowering action of Red Yeast Rice. Its active constituents include monacolin K, dihydromoncolin, and monacolin I to VI.
Red Yeast Rice is more efficacious than some synthetic cholesterol lowering drugs. In one of the trials comparing the effects of Red Yeast Rice and another synthetic cholesterol lowering drugs, subjects with high cholesterol were given either 2,400mg of Red Yeast Rice or 20mg of Pravacol. 12 weeks later, Red Yeast Rice was not only found to be more effective, it was also better tolerated than cholesterol lowering drug.
While cholesterol lowering drugs will only lower LDL - Unived's RYR effectively reduces LDL (bad) cholesterol as well as triglyceride levels and improves HDL (good) cholesterol levels.
RYR is proven to increase HDL levels by 14-20%.
Synthetic cholesterol lowering drugs are popularly prescribed to treat individuals with high cholesterol, due to their cholesterol lowering effect.
Unived's RYR contains Red Yeast Rice that is free from citrinin and any other impurities. Red Yeast Rice and therapeutic lifestyle may oﬀer a lipid lowering option for treating patients with a history of cholesterol lowering drug therapy intolerance.
Red Yeast Rice contains 0.4% monacolin K which is similar in structure and function to cholesterol lowering drugs but is free from the associated side-effects. Unived's RYR has no known side-effects.
There are several Red Yeast Rice manufacturers in the market, however, not all products are safe for your consumption. Before you buy, you need to make sure that the product is citrinin free and verify the percentage of monacolin K present in it. The wrong product can leave you suffering with several side effects instead of solving your health issues.
Unived's RYR is 100% natural and vegan & vegetarian and it is registered by the Vegan Society – UK, free from impurities. It has no wheat gluten, soy protein, milk/dairy, corn, starch, sugar, sodium, artificial coloring, preservatives or flavoring.
Daily intake of RYR – standardized Red Yeast Rice – assists you in managing your cholesterol without the adverse effects attributed to cholesterol lowering drugs. Each capsule contains 600mg of Red Yeast Rice standardized to 0.4% monacolin K - the international standard for cholesterol lowering Red Yeast Rice.
2400mg of standardized Red Yeast Rice is the ideal dosage to lower LDL and triglycerides, and increase HDL.
As a dietary supplement, we recommend you consume two vegetarian capsules, twice a day. This gives you 2400mg of Red Yeast Rice every day – the required dose for effective cholesterol management.
We do not recommend you to consume RYR, if you are already consuming synthetic cholesterol lowering drugs. You must first stop the consumption of cholesterol lowering drugs, and then begin RYR. It is not recommended to take cholesterol lowering drugs & RYR together.
If you are pregnant, nursing, breast-feeding; or if you are undergoing any serious medical complications, please do not consume any products on your own without the full knowledge and guidance of your doctor/physician.
We recommend you consult your physician before starting RYR.
Red Yeast Rice is a unique produce of culture, an ideal example of how natural remedies are embedded in our traditional culinary practices. A staple diet in many Asian countries, Red Yeast Rice is used to make rice wine, for flavor, and to preserve the flavor and color of fish and meat. Inherent to Chinese cuisine for centuries, Red Yeast Rice has also been used as medicinal food to promote 'blood circulation'.
Red Yeast Rice finds a cultural reference in 'koji', a Japanese word which implies a grain or bean allowed to overgrow with a mold culture. Koji is a mold culture prepared by growing either Aspergillus oryzae or Monascus purpureus mold on cooked grains or soybeans in a warm, humid place. Koji serves as a source of enzymes that break down natural plant constituents into simpler compounds when making miso, soy sauce, sake, amazake, and other fermented foods.
An increasing number of practitioners across the world, particularly in the US and Europe ascribe significant cholesterol-lowering properties to Red Yeast Rice. Several clinical observations in the last decade have shown Red Yeast Rice to be effective in lowering blood-lipid levels.
In his book 'Eat to Live', Joel Fuhrman MD, says about cardiovascular diseases, 'Every heart attack death is even more of a tragedy because it likely could have been prevented.'
High cholesterol or Hypercholesterolemia (also referred to as hyperlipidemia), is a leading risk factor for cardiovascular diseases and its symptoms are seldom manifest until the serum lipid levels are severely elevated and cross the range at which cardiovascular morbidity and mortality are increased.
Epidemiologic studies predict that for each 1% reduction in the level of LDL cholesterol there is a 1% to 1.5% reduction in the risk of major cardiovascular events. Well tolerated lipid-lowering therapies, along with lifestyle modifications go a long way in helping individuals maintain healthy lipid levels.
Young adults and working professionals
Hyperlipidemia is affecting millions of young people, the world over. Hypercholesterolemia is one of the major risk factors for atherosclerosis and coronary heart disease. They encounter multiple co-morbidities due to abnormal lipid-levels in their blood. To treat these, a majority of them are prescribed with cholesterol lowering drug therapy.
Leading cardiologist Dr. Stephen Sinatra is not in favor of using cholesterol lowering drugs, '…they have horrific side effects… If you treat a woman in her 30s just for "high cholesterol," and treating numbers, I think we're doing a disservice… We really shouldn't use them in elderly people. We shouldn't use them in young people, or in women. I have been very disappointed as a clinical cardiologist in the efficacy of cholesterol lowering drugs in women, even with advanced coronary disease.'
Since vegans follow a plant only nutritious diet, the dietary factors relating to the occurrence of high cholesterol are reduced to a minimum. So you are on a much better ground, as far cholesterol is concerned, as compared to meat and dairy eaters.
In India, cardiovascular diseases are a major public health concerns. Ethnicity is one of the determinants of absolute risk of coronary disease for given levels of cholesterol and Asian-Indians have the highest risk.
When are you predisposed to high cholesterol genetically? Medical practitioners use the term familial hypercholesterolemia (FH) to indicate the condition of high cholesterol being passed down to you through your family members. It is one of the risk factors that you cannot control since it is not due to external factors such as unhealthy lifestyles, but to genetics.
You are more likely to have high cholesterol:
Smoking destroys your health in many ways. Causing cholesterol related complications is one of them.
Cholesterol is a type of lipid (fat) substance made in the liver. Your body needs cholesterol in order to perform certain functions. The adrenal glands use it to form hormones such as cortisol, testicles use it to form testosterones and ovaries it use to form estrogen and progesterone. Cholesterol is also required to produce vitamin D and bile acids to aid digestion and for cell formation and repair. The cholesterol levels in the blood are required to be in proportion to the body's requirement. They begin to spoil your body's balance if they cross the healthy levels. Cholesterol is transported in the blood stream as lipoproteins.
Lipids are mobile in the bloodstream as 'lipoproteins'. These lipids include cholesterol, cholesterol esters, phospholipids, and triglycerides. Lipids are transported in the blood as large 'lipoproteins'. Hyperlipidemia is a condition wherein the lipid levels in the blood are higher than normal. It is also called as hypercholesterolemia.
LDL cholesterol, the cholesterol carried in LDL particles, is the 'bad' cholesterol. When elevated, LDL cholesterol can promote coronary artery disease. HDL cholesterol, the cholesterol carried in HDL particles, is the 'good' cholesterol. It protects against coronary artery disease.
Hyperlipidemia involves an excess of lipids (fat content) in the bloodstream. The major lipids in the bloodstream include cholesterol, phospholipids, triglycerides and cholesterol esters. Lipids are mobile in the bloodstream as 'lipoproteins'. When you check your serum lipid profile you will find that it gives you a report of the 'total cholesterol', LDL (bad) cholesterol, HDL (good) cholesterol, and triglyceride levels in your blood. A healthy lipid profile is an important factor in cardiovascular health and hyperlipidemia is a major but modifiable risk element for causing coronary heart disease and atherosclerosis.
A cholesterol lowering drug is a drug that has a cholesterol lowering effect on your body. They are a class of medicines used to lower your blood cholesterol levels. They do this by inhibiting the HMG-Co-A reductase enzyme which plays a key role in cholesterol synthesis.
Red Yeast Rice is an ancient Chinese medicine that has cholesterol lowering properties. It is prepared by fermenting rice, using a mold culture of red yeast or Monascus purpureus. It is reddish purple in color and acquires the same from the yeast. The use of Red Yeast Rice as part of cuisine has been culturally prevalent since 300 BC. Referred to as honqu (Chinese) or Ben koji (Japanese), it also finds mention in ancient Chinese pharmacological texts as having medicinal use.
Red Yeast Rice became known in the dietary supplements market in the late 70s when monacolin K was isolated from it. Monacolin K is similar in structure to a specific cholesterol lowering drug. It is responsible for the cholesterol lowering action of Red Yeast Rice and does so by blocking the action of HMG-Co-A reductase enzyme, a key element in cholesterol synthesis.
Unived uses standardized Red Yeast Rice that is fermented with the yeast Monascus purpureus consisting of the active compound monacolin K. Unived RYR – standardized Red Yeast Rice – is fermented in a facility that holds approval from various certifying authorities such as ISO 9001, GMP, HACCP, and USDA organic. The facility is approved by one of the world's leading verification, inspection, testing, and certification services company – SGS, headquartered in Geneva, Switzerland.
Although synthetic cholesterol lowering drugs effectively lower cholesterol levels in your blood, they also have a host of negative side effects including muscle pain, memory loss and CoQ10 depletion. In case of long term use, the muscular degeneration could turn much graver and lead to conditions such as myalgia and rhabdomyolisis.
Red Yeast Rice is a natural alternative to cholesterol lowering drugs and lowers cholesterol with more efficacy. Further, it is better tolerated by the body than the synthetic cholesterol lowering drugs. Unived's Red Yeast Rice is 100% free of citrinin and has 0.4% monacolin K which is the key ingredient that lowers cholesterol in the blood. Unived's RYR has no side-effects.
Unived's RYR is standardized, vegan and packaged in vegetarian capsules.
Majority of the products you find in the market use gelatin based capsules (derived from animal fat and cow bones). These can be hazardous to health as they may carry toxins and diseased animal tissues due to unsafe manufacturing practices, leading to mad cow disease and other health issues. Unived uses 100% vegetarian capsules that are made from cellulose of plants.
The vegetarian capsules are packaged in DMF grade HDPE bottles – this is the highest quality of packaging in the industry and is made from completely virgin HDPE. Our bottles are manufactured at a facility that is registered with the US FDA, Canadian FDA, and is ISO 9001-2008 certified.
Unived RYR – standardized Red Yeast Rice – is 100% natural, and completely citrinin free. This product contains no wheat gluten, milk/dairy, soy protein, corn, sugar, sodium, starch, artificial coloring, preservatives, animal products, or flavoring. Unived respects animal rights and does not undertake animal testing for its products.
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